Publications

Mahdavi M, Findlay BL. (2024) Discovery of an adjuvant that resensitizes polymyxin B-resistant bacteria . Bioorg Med Chem. 97:117541. doi: 10.1016/j.bmc.2023.117541. (pdf)

Chowdhury FR, Findlay BL. (2023) Fitness Costs of Antibiotic Resistance Impede the Evolution of Resistance to Other Antibiotics. ACS Infect Dis. 9:1834-1845.
doi: 10.1021/acsinfecdis.3c00156. (pdf) (Agence Science-Presse) (Concordia News)

Lander AJ, Mercado LD, Li X, Taily IM, Findlay BL, Jin Y, Luk LYP. (2023) Roles of inter- and intramolecular tryptophan interactions in membrane-active proteins revealed by racemic protein crystallography. Commun Chem. doi: 10.1038/s42004-023-00953-y

Ali DA, Domínguez Mercado L, Findlay BL, Badia A, DeWolf C. (2023) Opposites Attract: Electrostatically Driven Loading of Antimicrobial Peptides into Phytoglycogen Nanocarriers. Langmuir. doi: 10.1021/acs.langmuir.2c01794

Zaroubi, L., Ozugergin, I., Mastronardi, K., Imfeld, A., Law, C., Gélinas, Y., Piekny, A., Findlay, B.L. (2022) The Ubiquitous Soil Terpene Geosmin Acts as a Warning Chemical. Appl. Environ. Microbiol. https://doi.org/10.1128/aem.00093-22 (pdf) (Summary in Science) (Quebec Science) (The Scientist) (Concordia News)

Huang, H.Y., Skripka, A., Zaroubi, L., Findlay, B.L., Vetrone, F., Skinner, C., Oh, J.K., Cuccia, L.A. (2020) Electrospun Upconverting Nanofibrous Hybrids with Smart NIR2 Light-Controlled Drug Release for Wound Dressing. ACS Appl. Biomat. 3: 7219-27. (acs.org)

Victoria, F., Manioudakis, J., Zaroubi, L., Findlay, B., Naccache, R. (2020) Tuning residual chirality in carbon dots with anti-microbial properties. RSC. Adv. 10: 32202. (rsc.org)

Ghaddar, N., Hashemidahaj, M., Findlay, B.L. (2018) Access to high-impact mutations constrains the evolution of antibiotic resistance in soft agar. Sci. Rep. 8: 17023. (pubmed) (pdf)

Findlay, B. (2016) The Chemical Ecology of Predatory Soil Bacteria. ACS Chem. Biol. 11: 1502-10. (pubmed) (pdf)

Cochrane, S., Findlay, B., Bakhtiary, A., Rodriguez-Lopez, E., Vederas, J. (2016) The Antimicrobial Lipopeptide Tridecaptin A1 Selectively Binds to Gram-Negative Lipid II. Proc. Natl. Acad. Sci. 113: 11561-6. (pubmed)

Domalaon, R., Findlay, B., Ogunsina, M., Arthur, G., Schweizer, F. (2016) Ultrashort cationic lipopeptides and lipopeptoids: Evaluation and mechanistic insights against epithelial cancer cells. Pept. 84:58-67. (pubmed)

Guchhait, G., Altieri, A., Gorityala, B., Yang, X., Findlay, B., Zhanel, G., Mookherjee, N., Schweizer, F. (2015) Amphiphilic Tobramycins with Immunomodulatory Properties. Angew. Chem. Int. Ed. Eng. 54: 6278-82. (pubmed)

Li, J., Chaytor, J., Findlay, B., McMullen, L., Vederas, J. (2015) Identification of Didecyldimethylammonium Salts and Salicylic Acid as Antimicrobial Compounds in Commercial Fermented Radish Kimchi. J. Agric. Food Chem. 63: 3053-8. (pubmed)

Bai, Y., Findlay, B., Sanchez-Maldonado, A., Schieber, A., Vederas, J., Gänzle, M. (2014) Novel pyranoanthocyanidins and vinylphenol adducts of deoxyanthocyanidins in sorghum sourdough. J. Agric. Food Chem. DOI: 10.1021/jf503330b. (pubmed)

Cochrane, S., Findlay, B., Vederas, J., Ratemi, E. (2014) Residues in Octyltridecaptin A1 Analogs Linked to Stable Secondary Structure in the Membrane. ChemBioChem. 15:1295-9.
Findlay, B., Mookherjee, N., Schweizer F. (2013) Ultrashort Cationic Lipopeptides and Lipopeptoids Selectively Induce Cytokine Production in Macrophages. PLOS ONE. 8: e54280. (pubmed)

Findlay, B., Szelemej, P., Zhanel, G.G., Schweizer F. (2012) Guanidinylation and Tail Effects in Cationic Antimicrobial Lipopeptoids. PLOS ONE. 7: e41141. (pubmed)

Bera, S., Dhondikubeer, R., Findlay, B., Zhanel, G.G., Schweizer F. (2012) Synthesis and Antibacterial Activities of Amphiphilic Neomycin B-based Bilipid Conjugates and Fluorinated Neomycin B-based Lipids. Molecules. 17: 9129-9141. (pubmed)

Findlay, B., Zhanel, G.G., Schweizer F. (2012) Investigating the Hydrophobic Antimicrobial Peptide “Window of Activity” using Cationic Lipopeptides with Hydrocarbon and Fluorocarbon Tails. Int. J. Antimicrob. Agents. 40: 36-42. (pubmed)

Findlay, B., Zhanel, G.G., Schweizer F. (2012) Neomycin-phenolic conjugates: Polycationic amphiphiles with broad-spectrum antibacterial activity, low hemolytic activity and weak serum protein binding. Bioorg. Med. Chem. Lett. 22:1499-1503. (pubmed)

Zhanel, G.G., Lawson, C., Zelenitsky, S., Findlay, B., Schweizer, F., Adam, H., Walkty, A., Rubinstein, E., Hoban, D., Lynch, J., Karlowsky. J. (2012) Comparison of the Next Generation Aminoglycoside Plazomicin (ACHN-490) to Gentamicin, Tobramycin, and Amikacin. Expert Rev. Anti. Infect. Ther. 10: 459-73. (pubmed)

Findlay, B., Zhanel, G.G., Schweizer, F. (2010) Cationic amphiphiles: A new generation of antimicrobials inspired by the natural antimicrobial peptide scaffold. Antimicrob. Agents Chemother. 54:4049-4058. (pubmed)